The MAF/VE tables (and other tables) have to be good so the correct engine torque is calculated (I'm not sure how the ECM communicates to the TCM)... this ensures that base pressure is up.
The shift pressures have to be up, the shift times have to be down, the shift torque reduction has to be tuned to balanced to protect the driveline.
The computer is actually pretty good, it electronically does the same job as the vacuum modulator kit... but see other comments above.Also been told that whatever you do with a 4L65, the computer is the limitation and it would be a good idea to look at installing the sonnax vacuum kit to take it out of the equation (you have to fool it into thinking it is doing the job though).
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You may need to install a shift kit toincrease the mechanical/hydraulic line pressure... but at the same time you have to watch the maximum line pressure.
If you look at the hydraulic schematics, you will see that the TCM controls the PCS solenoid which regulates "Torque Signal" hydraulic fluid pressure... Torque Signal pressure assists the pressure regulator via the boost spring... i.e. Torque Signal pressure adds to the mechanically/hydraulically controlled line pressure...
But, please do get several opinions on this from as many sources as you can.