Ok, what firmware/bootblock are you currently using on your V2?
After a certain bb/fw, you need to use the EFILive Control Panel application to flash and NOT the V2 Programmer software (was released initially so we could program the V2 before the V8 stuff was released).
First, make sure you're running the latest and greatest software (V7.5.7 build 204 and V8.2.1 build 195) from the main downloads page Link to EFILive Software Downloads.
Try this, plug your V2 in, open V8 Scan & Tune, then click the little V2 icon that pops up near the windows clock. Then click F6 Firmware, click Update BootBlock. Wait for your V2 to enter dead-poll (2 amber LEDs flashing alternately), then click Update Firmware. Should program then reboot your V2, then you can use V8 to read/flash. Also you need to recopy all of your BBX settings if you're using any of the standalone reading/flashing/scanning features.