Do I change when going from stock 26 or 28 lbs. injectors to 60 lbs. Mototrons?

I know that I have to change the IFR table (with the calculations done using Red Hard Supras injectors.xls ss), but what else do I change?

I've read quite a few things on other forums that gives me conflicting advice and just confuses me (which isn't that hard ).

Any information would be Greatly Appreciated!

Thanks and Please Have a Merry Christmas and a Happy and Safe New Year!