Dreaded knock.... cant seem to get my tune right

[Dopey]

Hey Guys,
Kudos to the great forum and masses of information it holds

I have been lurking on here for ages trying to learn as much as I can to get my tune right, but I feel that it is above my head at the moment... The more I play some things become spot on, but then I start having other problems.. lol.

Any way, I have been messing around with my tune (attached) which was tuned by someone else but has always been problematic, knock and afr's jump all over the place. I feel that I have got the VE pretty much bang on, however I have been very cautiously playing with the 02 Dynamics to try and get rid of the spikes and knock on throttle stabs.

I have attached my tune and a decent sized log where you can see there is knock all over the place, yet when I compare my timing to others and even stock it seems very conservative?

*Note* please ignore the AFR spikes to 10 and >16 ever since I changed my PLX TTL to 232 circuit from my external MAX232 board to the small board off ebay featured in one of the stickies it has started spiking... I think the regulator on the board hasnt got enough puff to power the ttl converter and the PLX unit.

Any tips or help would be greatly appreciated

Car:
Holden VX SS M6

Alloy OTR
85mm ported throttle body
LS6 manifold with ported neck to suit TB
Magnecore 8mm leads
Tri-y headers
2x 3" High flow metal cats
Twin 2.5" Xforce cat back
4.11 Diff
PCV vents via a filter (ditched the catch can setup)
Copper NGK plugs