Try this:

Quote Originally Posted by Blacky View Post
Error $0280: Unsupported protocol (i.e. no vehicle detected)

Cause:
FlashScan or AutoCal could not detect a valid OBD protocol.

Action:
Check all cables and connections.
Make sure ignition is turned on to the run position.
Make sure the vehicle is supported by EFILive.

Some more things to try:
Turn ignition on first, wait 10 seconds, then connect FlashScan.
Press Ctrl+OK 2 or 3 times per second until you see the VPW-XX or CAN-XX in the lower right corner of the FlashScan display. (Where XX is the number of detected controllers).

Try FlashScan in a different vehicle. If it still fails then maybe there is a problem with the OBDII cable or with FlashScan itself.

Regards
Paul